2-O-Methylmagnolol, a Magnolol Derivative, Suppresses Hepatocellular Carcinoma Progression via Inhibiting Class I Histone Deacetylase Expression

Magnolia officinalis is widely used in Southeast Asian countries for the treatment of fever, headache, diarrhea, and stroke.Magnolol is a phenolic compound extracted Tabletop Decor from M.officinalis, with proven antibacterial, antioxidant, anti-inflammatory, and anticancer activities.In this study, we modified magnolol to synthesize a methoxylated

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A Novel Contrastive Self-Supervised Learning Framework for Solving Data Imbalance in Solder Joint Defect Detection

Poor chip solder joints can severely affect the quality of the finished printed circuit boards (PCBs).Due to the diversity of solder joint defects and the scarcity of anomaly data, it is a challenging task to automatically and accurately detect all types of solder joint defects in the production process in real time.To address this issue, we propos

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Rapid eye movements during sleep in mice: High trait-like stability qualifies rapid eye movement density for characterization of phenotypic variation in sleep patterns of rodents

Abstract Background In humans, rapid eye movements (REM) density during REM sleep plays a prominent role in psychiatric diseases.Especially in depression, T-Shirts an increased REM density is a vulnerability marker for depression.In clinical practice and research measurement of REM density is highly standardized.In basic animal research, almost no

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